петак, 7. септембар 2012.

Autoimmune Disease – Alopecia Areata

Autoimmune Disease – Alopecia Areata
Alopecia areata is a disease that affects the hair follicles, which are part of the skin from which hairs grow. In most cases, hair falls out in small, round patches about the size of a quarter. Many people with the disease get only a few bare patches. Some people may lose more hair. Rarely, the disease causes total loss of hair on the head or complete loss of hair on the head, face, and body. Anyone can have alopecia areata. It often begins in childhood. There is a slightly increased risk of having the disease if you have a close family member with the disease.
Alopecia areata is an autoimmune disease. Normally the immune system protects the body against infection and disease. In an autoimmune disease, the body's immune system mistakenly attacks some part of your own body. In alopecia areata, the immune system attacks the hair follicles. The cause is not known. Scientists think that a person's genes may play a role. For people whose genes put them at risk for the disease, some type of trigger starts the attack on the hair follicles. The triggers may be a virus or something in the person's environment.
There is every chance that your hair will grow back, but it may fall out again. No one can tell you when it might fall out or grow back. You may lose more hair, or your hair loss may stop. The hair you have lost may or may not grow back. Even a person who has lost all of his hair may grow all of his hair back. The disease varies from person to person. Here are some treatments for alopecia . Corticosteroids:
Corticosteroids are drugs that reduce swelling and pain. They also affect the immune system. Corticosteroids may be given in three ways for alopecia areata:
• Injected in the skin • Swallowed as pills • Rubbed on the skin as a cream or ointment. Drugs that are rubbed on the skin as a cream or lotion include: • Minoxidil (5%) • Anthralin • Squaric acid dibutyl ester (SADBE) and diphenylcyclopropenone (DPCP). Drugs that affect the immune system include: • Sulfasalazine • Cyclosporine.
Photochemotherapy:
In photochemotherapy, a person is given a drug called a psoralen, which is affected by light. The drug can be swallowed or rubbed on the skin. Once the drug is taken or applied, the area with hair loss is exposed to an ultraviolet light source. This combined treatment is called PUVA.
Alopecia areata does not make you feel pain and does not make you feel sick. You can't give it to others. People who have the disease are, for the most part, healthy in other ways. Alopecia areata will not shorten your life, and it should not affect activities such as going to school, working, marrying, raising a family, playing sports, and exercising.
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